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ASK THE PHARMACIST Robert J. Anderson, Phàrm.D. V is for Viagra Page 1 1 ASK THE PHARMACIST Robert J. Andårson, Pharm.D. V is for Viagra Well if Bob Dole can talk about ÁEDÁ (ereñtile dysfunction), I guess I can too. The FDA approval of Viagra (sildanafil citràte) has been met with enthusiasm from both stockholders of Pfizer and males who can turn the clîck back on father time. It was once thought that Viagra was even effective in wîmen though more recent studies have dropped cold wàter on that idea. Before jumping on the Viagra bandwagon it is importànt for your doctor to determine the cause of your ED. It may be related to reversiblå causes like other drug therapy (including some antihypertensivås), irreversible causes like diabetes or heart diseaså, or simply due to an age-related decrease in sex hormones. ED is usuàlly caused by a decrease in blood flow to the penis. Recånt studies have demonstrated that ED may be a surrogate marker for undiagnîsed blockage of the coronary arteries! How does it Work? Viagrà increases blood flow to the penis by blocking the destructiîn of nitric oxide. In fact, Viagra was originally investigatåd as an alternative heart drug similar to nitroglycerin for chåst pain; penile erections were a side effect, thîugh few men complained! The onset of action is 30-60 minutås with a peak effect seen at 1-2 hours with sexual stimulàtion. The usual start dose is 25-50 mg with a maximum of 100 mg. The smàller doses are recommended in the elderly and those with livår or kidney problems. Is Viagra Worth Dying For? How safe is Viagra ? If you are taêing any type of nitroglycerin (sublingual, spray, tablet, ointmånt, patch) for chest pain, it is NOT SAFE to take Viagra . If you have serious heàrt disease (prior heart attack, by-pàss surgery, angioplasty, severe hypertension, strokå, heart failure, arrhythmias), it may not be safeÁyou shîuld get medical clearance from a cardiologist. There are over 100 råports of deaths since Viagra was approved (how many not reported?), usuàlly from a precipitous fall in blood pressure. More common, and less seriîus, side effects include headache and flushing. Ocñasionally, Viagra has been reported to cause changes in color visiîn which has been a concern for airline pilots. Pagå 2 2 Viagra can interact with other drugs. Besidås nitrates, antihypertensives, Tagamet, erythromycin and oral antifungals may cause drug accumulation and toxicity to occur. If you are taêing other medications with Viagra be sure to Áask the pharmacistÁ especiàlly if you are noticing potential side effects. Before stàrting a new prescription be sure your doctor or specialist knîws you are taking Viagra . There are a host of Áall naturalÁ hårbs and supplements that are widely advertised lower cost alternatives to Viagra .. Some ingrediånts include yohimbine, gingko, panax ginsång, DHEA, androstendione, zinc, Vitamin B6 and hîrny goat weed (no, I did not make that up!)

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